Because it is professional gear, the "software" isn't a user-friendly GUI. It is —a dense, Windows XP-era database application that communicates via a serial-to-USB converter (specifically a Prolific PL-2303 or FTDI chip).
The CE59 software is designed for both mobile and handheld radio series, including: VX-4100 and VX-4200 series. Vertex Ce59 Software Download
Vertex Standard CE59 is the official Windows-based programming software used to configure frequencies, signaling, and functions for several series of professional two-way radios. Core Purpose & Capabilities Because it is professional gear, the "software" isn't
: Requires team approval for software purchases, usually handled during business hours. Because it is professional gear
Open "Device Manager" on your PC and look under "Ports (COM & LPT)" to see which port number (e.g., COM3) your cable is using.