This error is most common on modern versions of Windows (Windows 10 and 11) trying to run the older 2009 PC port.
Alternatively, edit the config file:
If the game refuses to boot because it is trying to force a broken full-screen environment, you can bypass it by editing the game's configuration file. Navigate to your PC's documents folder (usually C:\Users\YOUR_USERNAME\Documents\CAPCOM\RESIDENT EVIL 5 config.ini file with Notepad. Look for the line that says FullScreen=ON and change it to FullScreen=OFF Save the file and try launching the game. re5dx9.exe fatal application exit
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