Abiotrophia , Granulicatella , Aerococcus , Gemella , and the (H)ACEK group.
In the complex world of clinical microbiology, most labs are well-versed in the "big three" documents from the Clinical and Laboratory Standards Institute (CLSI) : M02, M07, and the ubiquitous M100. But what happens when you encounter an organism that isn't a "usual suspect"? That’s where comes in.
This article provides a deep dive into the M45 document—its purpose, history, key content, how to obtain a legitimate PDF, and why it remains the "gold standard" for unusual organism testing.